CLOMO
(Instructions for medical use of therapeutic agents)
Registration number Mfg: HP/DRUGS/PP-682/2SA.
Active ingredient: Сlomiphene citrate.
Packaging: Blister pack of tablets.
Dosage: 50 mg/tab of Clomiphene citrate.
Category drugs: Antiestrogen.
Рharmachologic effect: Gonadotropin production stimulator. Means with antiestrogenic and estrogenic activity. Has a non-steroidal structure, which is close to chlorotrianisene. It is believed that the effect of clomiphene is due to specific binding to the estrogen receptors of the hypothalamus and pituitary gland, which increases the secretion of gonadotropic hormones of the pituitary gland. This in turn stimulates the maturation and endocrine activity of the follicle in the ovary, as well as the subsequent formation and stimulation of the function of the corpus luteum. In high doses, inhibits the secretion of gonadotropins. It does not have gestagenic and androgenic activity.
Indications: To stimulate ovulation in infertility due to secondary hypofunction of the ovaries, mainly due to functional hypothalamic-pituitary disorders; functional uterine bleeding; secondary amenorrhea or severe oligomenorrhea; polycystic ovary syndrome (such as Stein-Leventhal); androgen deficiency; in men - oligospermia.
Dosage: Take orally. A single dose is 50 mg. Multiplicity of admission is set individually, depending on the indications, treatment regimen and effectiveness of therapy.
Side effect: From the side of the central nervous system: increased irritability, fatigue, dizziness, insomnia, severe headache.
From the endocrine system: weight gain, polyuria, pollakiuria, increased sweating, an increase in the size of the ovaries or ovarian cysts, pain in the area of the uterine appendages, heavy menstruation.
From the digestive system: a feeling of heaviness in the epigastrium, flatulence, nausea, vomiting.
Allergic reactions: urticaria, allergic dermatitis.
Other: heat attacks, heaviness in the chest, slight reversible alopecia, impaired visual acuity.
Contraindications: Impaired liver function, visual impairment (including a history), ovarian cysts, neoplasms, primary pituitary pituitary, bleeding of unknown origin, pregnancy, lactation, hypersensitivity to clomiphene.
AllChem Asia
(GMP Certified company)
Pharma City Road, Selakui,
Uttarakhand 248011, India